Essential Blood Tests You Should Get Annually (and Why They Matter)

Laboratory studies are important for telling us more about our health. They provide vital insights into where you stand and help you stay on top of potential issues. While lab tests are just one piece of the puzzle, when paired with a physical examination and a thoughtful discussion with your healthcare provider, they give you the tools you need to take charge of your health and make informed decisions.

In today’s fast-paced world, where we are juggling full-time jobs, parenting, social obligations, side hustles, and the demands of staying connected in a digital age. With so much on our plates, it can be easy to put our own health on the back burner. It’s no surprise that certain health presentations are common. Take the following patients as examples:

  • Sarah is a 39-year-old marketing executive, often starts her mornings feeling unusually tired, despite getting a full night’s sleep. She’s noticed weight gain over the past few months and is wondering if her hormones might be to blame.

  • James, a 46-year-old software engineer, has recently been reading about how heart disease runs in families. With a father who had a heart attack at 55, James is determined to stay proactive about his health.

    Both Sarah and James decide it’s time for their annual check-ups, but they’re unsure on how to address their specific concerns and prevent potential health issues.

Why Annual Lab Testing Matters:

Annual laboratory tests play a crucial role in maintaining health by detecting underlying conditions before symptoms appear, monitoring existing health issues, guiding lifestyle and medical interventions, and providing a benchmark for future comparisons. By understanding what tests are needed at different stages of life, you can ensure optimal health and longevity. Regular laboratory testing is essential for adults at all stages of life to monitor overall health, detect underlying conditions, and guide preventive care.

Recommended Annual Labs:

Below is a general outline of the key tests that are recommended annually for adults:

  • Complete Blood Count (CBC): Screens for anemia, infections, and other blood disorders.

  • Comprehensive Metabolic Panel (CMP): Assesses kidney and liver function, blood sugar, and electrolyte balance.

  • Lipid Panel: Measures cholesterol levels (total, HDL, LDL, triglycerides) to evaluate cardiovascular risk.

  • Hemoglobin A1c (or fasting glucose): Monitors average blood sugar levels over three months to screen for prediabetes or diabetes.

  • Vitamin D Levels: Evaluates bone health and immune function.

  • Vitamin B12 Levels: Assesses deficiencies that can affect nerve function, energy levels, and cognitive health.

  • Fasting Insulin: Helps detect early signs of insulin resistance and metabolic syndrome.

  • Thyroid Panel (TSH, Free T4, Free T3, TPO antibodies): Detects thyroid dysfunction; a comprehensive thyroid panel is especially critical for women to assess hormonal imbalances and symptoms such as fatigue or weight gain.

Additional Considerations Based on Specific Concerns:

There are additional tests to consider based on age and specific health concerns, which can provide deeper insights into your overall health:

  • Women in Perimenopause and Menopause: For women experiencing symptoms of perimenopause or menopause, hormonal testing can be a valuable diagnostic tool. It is essential to discuss with your healthcare provider which tests are most appropriate based on your symptoms. Hormonal testing may include Estrogen, Progesterone, Follicle-Stimulating Hormone (FSH), and Luteinizing Hormone (LH) to assess symptoms such as irregular periods, hot flashes, and mood changes.

  • Women with heavy menstrual cycle or anemia on CBC: It is imperative to add Iron Studies/Ferritin to screen for iron deficiency anemia which is very common and can lead to symptoms of fatigue in menstruating women. Iron deficiency in non-menstruating women require a full workup to evaluate for the blood loss.

  • Men: For men, annual testing may include a Prostate-Specific Antigen (PSA) test, particularly for those aged 50 and older, or earlier if there is a family history of prostate cancer. While PSA testing is a valuable tool for detecting potential prostate issues, it is not perfect and can sometimes yield false positives or false negatives. Discussing the risks and benefits of PSA testing with a healthcare provider is essential to determine its appropriateness based on individual health and family history. Additionally, testing for Free and Total Testosterone levels can provide insight into energy levels, libido, and muscle mass changes, particularly for men experiencing symptoms of hormonal imbalance.

For Sarah: Based on her concerns and symptoms, she will benefit from a full thyroid panel, lipid panel, fasting insulin, and iron studies. These are essential in uncovering hypothyroidism, insulin resistance, and mild anemia, improving her energy and mood with appropriate treatment.

For James: Underwent a lipid panel, fasting insulin, and hemoglobin A1c which identified early insulin resistance and borderline cholesterol levels, which were addressed with lifestyle changes to improve his metabolic health.

Due to his family history of heart disease, it is particularly important for James to undergo advanced cholesterol testing to gain a more comprehensive understanding of his cardiovascular risk. This testing may include High-Sensitivity CRP (an inflammatory marker), Lipoprotein(a), Apolipoprotein B (ApoB), and lipid particle size analysis. Lipoprotein(a), or Lp(a), is a specific type of lipoprotein that carries cholesterol and fats in the blood. Elevated levels of Lp(a) are associated with a higher risk of atherosclerosis and heart disease, as it promotes plaque formation in the arteries. Similarly, Apolipoprotein B is a protein found in LDL particles (commonly known as “bad cholesterol”) and serves as an indicator of the number of atherogenic particles in the blood. Elevated ApoB levels are considered a strong predictor of cardiovascular disease.By identifying these markers, we can better assess not just the quantity but the quality and behavior of cholesterol particles, allowing for a more tailored approach to managing James's heart health and mitigating his risk of future complications. (Look out for a dedicated blog discussing cardiovascular risk testing and who needs them in detail within the next few weeks).

Take Control of Your Health:

Proactive lab testing tailored to your age, gender and symptoms can prevent and manage health issues before they become serious. Speak with your physician about customizing your annual labs based on your health history and lifestyle.

Your health is your wealth—invest in it wisely!

If you are interested in joining our primary care membership program, please CLICK HERE to review the benefits of our membership and ENROLL . Our primary care membership includes access to discounted laboratory studies and you can find out pricing HERE.

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